1. Many cancer drugs aim at the wrong molecular targets  Nature.com
  2. Some cancer drugs miss their target. CRISPR could improve their aim  Science Magazine
  3. Why Aren’t There Better Cancer Drugs? Scientists May Have Picked the Wrong Targets  The New York Times
  4. Study suggests explanation for why so many cancer drugs fail  STAT
  5. Many cancer drugs don't hit their intended targets: study  FierceBiotech
  6. View full coverage on Google News
Analysis using CRISPR gene-editing technology suggests that drugs’ mechanism of action are misunderstood. Analysis using CRISPR gene-editing technology suggests that drugs’ mechanism of action are misunderstood.Analysis using CRISPR gene-editing technology suggests that drugs’ mechanism of action are misunderstood.

Many cancer drugs aim at the wrong molecular targets

Method that generated drug leads may be flawedMethod that generated drug leads may be flawed

Some cancer drugs miss their target. CRISPR could improve their aim | Science | AAAS

Compounds being tested in patients might be useless, and a keystone of personalized medicine for cancer might be on shaky ground.Compounds being tested in patients might be useless, and a keystone of personalized medicine for cancer might be on shaky ground.

Study suggests explanation for why so many cancer drugs fail - STAT

“Targeted cancer drugs sound like magic bullets. But what if scientists get the target wrong? Here’s my story on a new study of these drugs for @nytimes https://t.co/mz74SDg6PK”

Carl Zimmer on Twitter: "Targeted cancer drugs sound like magic bullets. But what if scientists get the target wrong? Here’s my story on a new study of these drugs for @nytimes https://t.co/mz74SDg6PK"

“The dirty little secret of "targeted" cancer drugs--we don't *really* know what they're doing, which is why clinical trials are still so unpredictable. This study finds that some so-called targeted therapies are hitting totally different targets! https://t.co/K8eky2EDFN”

Kat McGowan on Twitter: "The dirty little secret of "targeted" cancer drugs--we don't *really* know what they're doing, which is why clinical trials are still so unpredictable. This study finds that some so-called targeted therapies are hitting totally different targets! https://t.co/K8eky2EDFN"

“"Why Aren’t There Better Cancer Drugs? Scientists May Have Picked the Wrong Targets"https://t.co/WYn0fjWl0N”

Rob Hopwood on Twitter: ""Why Aren’t There Better Cancer Drugs? Scientists May Have Picked the Wrong Targets"https://t.co/WYn0fjWl0N"

“A unique & hopeful cancer drug is approved, targets the mechanism that turns normal cellular to abnormal growth https://t.co/jPPx8knveS”

Cary Cooper on Twitter: "A unique & hopeful cancer drug is approved, targets the mechanism that turns normal cellular to abnormal growth https://t.co/jPPx8knveS"

Several cancer drug candidates in clinical trials are designed to kill tumor cells by attacking certain targets, but they actually work in other ways, a study by Cold Spring Harbor Laboratory has found.Several cancer drug candidates in clinical trials are designed to kill tumor cells by attacking certain targets, but they actually work in other ways, a study by Cold Spring Harbor Laboratory has found.

Many cancer drugs don't hit their intended targets: study | FierceBiotech